I just closed a case that I had open for 65 days. This was a very tough problem to troubleshoot and solve. Autodesk Simulation 2012 worked but Autodesk Simulation 2013 would crash on startup.
In the end the solution was quite simple, turn off the On-Screen Keyboard!
Thanks to Royce Abel & John Sauber confirming the this solution worked.
This issue is now resolved by installing Simuation CFD 2013 SP1. Please refer to this TS for details:
Thanks again to Royce Abel for providing an update on this interesting problem.