I have been using this Microsoft Fix it tool with some success this past week. In some instances, there is a problem in which you can't install the software after uninstalling it or there is transform error. Normally, we would hack the registry or use a 3rd party registry cleanup tool to try to resolve the issue.
Error applying transforms. Verify that the specified transform paths are valid. #222
1. Download Microsoft Fix it tool and use the Advanced Download option.
2. Download, run and extract Microsoft Fix it on the desktop of your computer.
3. Select Install or upgrade Software or Hardware category.
4. Go to Fix problems with programs that can't be installed or uninstalled.
5. Select Run Now.
Please check out a video demo of the workflow: