I love updates that are free but please update with caution! Any full point release [10.9] is pretty much a whole new operating system on the Mac.
If you are currently using Autodesk products on the Mac, please don't upgrade yet. There are some known issues noted below:
Maya LT 2014
Mudbox 2014 for Mac
AutoCAD 2013 for Mac
Autodesk Smoke 2013
Smoke 2013 is currently unsupported on 10.9.
As of October 23, 2013, AutoCAD & AutoCAD LT 2014 for Mac has just been released and it supports Mac OS X Maverick [10.9].
Please check out the Comments section for a note in this post for users of Maya 2014 & Mudbox 2014.